Etiology

 

The exact cause of SLE is unknown, but it is believed to be a combination of genetic and environmental factors.

  • Genetics - People with a family history of lupus are more likely to develop the disease. However, having a family history does not mean you will definitely get lupus.
  • Environment - Certain environmental factors, such as exposure to sunlight, viruses, and certain medications, may trigger lupus in people who are genetically predisposed to the disease.

Here's a breakdown of the factors that are believed to contribute to SLE:

  • Genetic predisposition - SLE is more common in people with certain genes, but these genes do not directly cause the disease.
  • Environmental factors - Sunlight exposure, infections, and certain medications can trigger lupus in people who are genetically predisposed.
  • Hormonal factors - SLE is more common in women, especially women of childbearing age. Hormonal changes, such as puberty, pregnancy, and menopause, may play a role in triggering or worsening lupus.

Researchers are still trying to understand the exact cause of SLE. However, understanding these risk factors can help doctors identify people who are more likely to develop the disease and take steps to prevent or manage it.

 

 

Systemic Lupus Erythematosus

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